120 from Lee Vining to Moccasin

I'm sure you can drive it but I wouldn't enjoy the drive if it were me. We chose to camp just inside the east edge of Yosemite at St Marys and drive the minivan to explore the area. That said, others have driven it in their rigs with no problem at all. I grew up driving in the flat lands of the mid west so it really gets down to your driving experience and your tolerance for tight turns, heights and possibly long lines of traffic behind you.