Just to stick with the specific points on your itinerary:
There are two good possibilities from Colorado Springs to Ouray:
1> Take US 24 West out of C.S. to the intersection with US 285 near Buena Vista, then 285 to US 50 West at Poncha Springs through Gunnison to Montrose where you take US 550 South into Ouray.
or
2> Take Colorado 115 to intersection with US 50 near Canyon City. From there stay on US 50 West as above.
I have been over both routes several times towing a 34' fifth-wheel trailer. I can't see any problem with these routes in July.
There would be nice overnight stops in Buena Vista and/or Gunnison, and Ouray is a great destination.
From Ouray to Vail you would take US 550 back north all the way to I-70 East at Grand Junction. Follow I-60 E. to Vail.
One possibility from Vail to Estes Park would be to pick up US 6 near Central City, then CO 119 North. This route is called the "peak to peak highway." It is very winding and up and down, but I always enjoy it. It will be slow but scenic. The highway number changes a couple of times as you get near Estes Park, but I won't go into that detail here. If you are interested, I'll be happy to respond to a PM.
I've never had much interest in Vail, but you may have good reason to make that a stop. Anyway, it's on the way to Estes Park.
Remember that Estes Park was devastated by floods last year; many roads were completely cut off. Be sure to check all that out before going into E.P.
Let me know if I can make further suggestions or comments.
