I've been looking at the maps. I think you are going to be very tired when you get home and have some very cranky kids along the way. I hope you are young (you must be with children between 5 and 11), because a trip like that would wipe me out fast and the kids would drive me nuts equally as fast. Personally, I think you should have some "down time" in there, unless you are use to driving 8-10 hours or more a day. The kids need to get out and do some exploring and playing on their own, not just sit and see the world through a windshield.
Have you asked the kids and wife what interests them and incorporate some activities that's tailored to their individual likes? Is the trip to be meaningful for you and they are along just for the marathon ride or to be meaningful for them?