It appears that the OP has a 38' 5th wheel. Hwy 1 is not recommended. Hwy 101 is more suited for him. If he doesn't have a destination of San Jose (like visiting family or whatever) then to avoid San Francisco traffic he could take 101 south to Hwy 20 to I-5 or go further south on 101 to Santa Rosa and pick up 12/29 (Napa) or go to Novato and take 37 east toward Napa and heading to I-80 to I-5. We've done all those routes with our 40' motorhome. If the OP wants to tour San Francisco, stay in Novato and drive to the Larkspur ferry taking it across the Bay ending at the Ferry Building Marketplace where he can board a small van for an awesome tour of the city, across the Golden Gate and have lunch in Sausalito. It's a very convenient way to see the city.
https://www.sanfranshuttletours.com/