I was born and raised in Alaska but hadn't been back since I left for college. When I retired I made my first trip back in my Class B without a toad. This year I made the trip back in the same Class B but towed my Jeep Wrangler with me. I didn't really need or use the 4-wheel drive, but it's my other vehicle. I did do a lot more exploring and travel with the Jeep (15,000 miles not including the drag up and back) than I had in the RV on my previous trip. So I'd say it depends on your camping style and how much exploring you want to do.
The Jeep was nice for the trips up the Dempster to Inuvit in the Yukon, the Top of the World Highway, Prudhoe Bay and Eagle, AK but I wouldn't have a problem driving those roads in my RV.
I will be going back again next year for a HS reunion and I'm seriously considering dragging the Jeep again. There are some places and side trips that are much cheaper and easier in a small vehicle vs an RV, such as exploring the the marine highway on the ferries. I was able to get squeezed onto the ferries even when they were booked full where folks with RVs sometimes had to wait for days to get a booking for a trip.