US Hwy 441 on the east side (take bypass to the west side of Athens). You can pick it up pretty much anywhere in GA. Try looking at an actual Map instead of following the rest of the sheep. Interstates are made for speed and convenience for travelers. RVers drag a self contained fully equipped hotel room with them. They do not need restsraunts and hotels.
There is also another US Hwy on the west side (goes thru Rome, Ga can't remember the name). I prefer to avoid interstates as much as possible. I have found that the US Highways tend to be just as fast (at my normal lower traveling speeds) and far more relaxing. I use The Next Exit to see what is at the interstate intersections that I pass over and the ones near to where I am passing.