Central Missouri to Colorado Springs

Appreciate all the advice everyone! I should have added that I have been to Colorado several times, I've just never towed anything out there :) Had in-laws out there during my first marriage, but haven't been back much since my first wife and I divorced. Taking my second wife and her daughter out so they can see why I love the state so much. A lot of the reason we upgraded our truck and travel trailer (had a '13 F150 SC 5.0 and 18 foot bunk house) was to go on camping trips farther away from Missouri. Very much looking forward to getting out there again. We had our campgrounds reserved a couple of months ago, and already have tickets for the cog ride up to Pike's Peak as well, so we are good there. I just needed to know what to expect as far as steep grades and narrow passes that could cause difficulty. It's one thing to drive in those areas, and a completely different thing to TOW in those areas. Glad there is such a wealth of knowledge on here to help ease my mind!