I-78 road work is at night, so you should be OK during the day. Now, having said that........
as noted in another reply to your post, I-78 sees LOTS of truck traffic. In spite of the fact that this end of I-78 in PA is a "TEA" (Targeted Enforcement Area) the 55 mph speed limit is rarely enforced. Traffic merging in from the ramps WILL pull right out in front of you. In some stretches you'll be doing 70 and only keeping up with "the flow." In May and June we had 4 accidents with fatalities, 3 of which involved trucks.
Personally, I hate this highway so if you use I-78 please be on your guard. If you are eastbound the dangerous interchange is at Rt. 100 in Fogelsville. Get in the left lane as soon as you see the brewery and stay there until after the I-78/Rt. 22 split. Be safe.