Destroy your unit? Could happen if you do not drive according to road conditions. In northern Canada and Alaska the roads have frost heaves. You can't drive 60 miles an hour. There's a stretch, say Whitehorse northward to Alaska, where you might be doing 30MPH or less because of road conditions. There's lots of great scenery to look at.
That said, if you have major time constraints you should consider flying in and renting a class C or doing the cruise ship.
We took all summer - took about two weeks to get there from SweetGrass Montana to Tok, Alaska. Some folks do that drive in 10 days.