Best time is Sunday morning around 9AMish > South to North, watch the lane markers and signs. The Downtown Connector splits back into I75 and I85 as you pass the major buildings downtown.
North to South > Keep toward the center lanes. For some reason the far left lanes will exit up a very short ramp and dead end to a left or right street. We had a tour bus with a athletic team run up one and off the bridge a few years back. People died from poor design.