Heading South From Indiana to FL AVOID ATL

Love DeSoto State Park. If you have the time, head to Birmingham and pick up 65 south like Whaler suggested. Deer Run is a really nice RV park on 231 if you don't want to drive all day. From there you are a short hop to I10 and lots of options along the panhandle if you want to drop down to the gulf along the way. After the panhandle I use US19 south along the West coast until cutting across to 75 well north of Tampa. 19 is four lane and light traffic until Crystal River. If you turn East at Chiefland, Williston Crossings is a super RV park, concrete pull thrus and reasonably priced. From there you are a short hop to I75 and an easy day to Bonita Springs. Try to avoid 75 around Tampa at rush hour just like you would any busy city. There is some construction but no delays in the Tampa area. Last fall there were some significant construction on 75 between Port Charlotte and Bonita Springs on my way to Marco, that caused a long backup, but it may have finished by now.