I took old 666 (now 191) from alpine to clifton-morenci some years ago in my pickup with slide in camper. As I recall 4 hours for a little over 150 miles. not fun to say the least. Great for a motorcycle ride however.
Go over in NM to grants go down 53 to 117 that way past Malpais lava flow go to Quemado, Pie town and either back to AZ or.... as noted above you will either need to go to I25 or over to 60/260 to globe. just all depends on final destination on 10.
BTW foirgot to add 191 from I40 south is a junk road, very rough in places. we did it with our TT 2 years ago, not a nice ride, no scenery etc. High plains is all it is.