Route 50 between Winchester and Clarksburg, WV is a very scenic 2 lane road.......if you're on a Harley! A lot of steep grades along with some pretty tight turns. An OK route out of Winchester is rte. 522 that will take you up to Hancock, MD where you can catch I-68 to Morgantown, WV then south on I-79 to Clarksburg where you can pick up rte 50 which is a good 4 lane into Ohio that will end up being rte 32 over to Cincinnati.