How you plan the trip depends on the objective. Is your objective to get to the west coast at all costs (fast and furious) or are your most interested in seeing the countryside (slow and steady).
I am assuming young children. My children when young did not appreciate driving 10-12 hours a day. Going to bed and doing the 10 - 12 hours again. They tolerated it poorly as the anticipation of the destination was what they focused on. (Disney)
That said the plan should include children's activities along the way. Whether as simple as stopping at a McDonalds play land etc. Do not emphasize the final destination or they may focus on that instead of enjoying the intervening miles. The children we have do not remember the trips we took when they were 4 and 5 years old but they REALLY REMEMBER and talk about the trips that they took with us when they were older.
Destination theme parks with young children is a drag on everyone. Nothing worse than traveling a long distance and having the children pooped out when they get to the destination. They are cranky, you are cranky and you all end up miserable. They need a nap, you want to see the park and have them enjoy the experience.
My advice stay close to home till children are older.