I-40 E to I-44E to I-70E? NM to VT

vtchris wrote:
I am asking the best way to get from Tucumcari, NM to Brattleboro, VT in these unusual days. Any hints from current travelers would be greatly appreciated.

"Best" is always subjective, depends on whether you want to avoid major urban areas or go a bit further out of the way to avoid them.

An alternative to the route you asked about, which includes some (3) major urban areas, would be to take I-40 all the way to Knoxville, TN and then pick up I-81 outside of Knoxville and take it north to I-84 in Scranton PA and then east to I-91 to Vermont. Yes, you have Memphis to go through, but there's a bypass (I-840) around Nashville, so Memphis would be the only real major urban area on this route.