Good summary by naturist. We lived in CO and did the route many times.
I would not worry about the road - it is interstate and grades limited (supposedly) to 6%; I think that is about right. And wide and all that. But you will be climbing to 11,000 feet a couple of times and I am wondering about your class C engine capabilities.
If it is gas you lose about 4% of the power with each 1000 foot elevation - that is what I have heard many times although I cannot document it. I will tell you we drove a rented class C, no toad, west from Denver many years ago (before we true rv'ers and understood mountain driving) and I actually stopped west of Denver to check and see if we had brakes that locked up and the engine was coming to near standstill!
You might have to disconnect the Fusion and drive it separately on occasion.
Also, not sure when you would be going to weather is definitely a factor.