I-75 from Florida to Ohio

I can't speak specifically to I-75 but we just came from Florida to New York State taking a different route. I'm sure the situations are similar regardless of the road traveled. The roads were busy near larger cities but I would guess there was about 40% of normal traffic everywhere else. Getting fuel wasn't an issue but finding places to stay ended up being a problem. We had planned on a slow trip home but it ended up being pretty quick. Private Campgrounds in Georgia, South Carolina and West Virginia cancelled our reservations so we had a couple of days where we had to drive farther than we wanted to. The campground in West Virginia called us 5 hours before we were going to arrive to tell us we couldn't stay there because the Governor had issued an order preventing out of state people from staying at campgrounds in that state. I would call the campgrounds you have booked to make sure you can still camp there. On the bright side, Rest areas had plenty of places to park and many truck drivers were using them to get much needed rest. The restrooms were also open. You likely won't be bothered if you get a few hours sleep in a rest area.