My wife and I are making the same trip. We are planning to leave from Seekonk Ma. on June 10. The route I have planned is: Home to Herkimer Diamond Mines KOA, then cross the border to Canada at Thousand Islands. Make our way to Canada Route 17 (trans Canadian highway) to Sault St Marie. Sault on Rt 28 to Bessemer Michigan then Route 2 to Glacier Nat. Park. We are going to camp there for a while before heading on to the west Coast. We chose this route because it avoids all the big city congestion and boring interstates. As has been said. Be sure your RV maintenance is up to snuff and you will be OK. There is so much to see and do there that if you feel uncomfortable about a situation there is always something else to do or see that is just as exciting.
When you get close, you could just ask your fellow campers, just like you are doing here. We got some great advise last year about local routes to use and sites to see.