Naples to Islamorada in the Keys

Agree on 41 to Krome and then south to US 1. As to the poster that suggests that I75 would be faster for your route, that would be wrong. From Club Naples, I 75 would dump you off on between N. Miami and Ft Lauderdale. You would have, at anytime of day, a good drive from there just to get as far south as to where US41 would take you at Krome.

Wave "hello" as you pass Port of the Islands about 16 miles east of Collier Blvd on 41.