Last summer I used 295 because of major construction delays on 95 in Richmond. Very little traffic and easy ride. I also prefer the I66, Rt 17 approach from 81 to 95. I used to drive I81 all the way to I77 or on down to Chattanooga, but the truck traffic seems to be worse every year. There are so many distribution centers on I81 now and they create lots of truck traffic. Also many manufacturing companies have relocated to the I81 corridor in the south. I95 has three lanes from Richmond to Florida except for a stretch in South Carolina. I81 is mostly two lane and often bumper to bumper with big trucks in both lanes. I used to avoid 95 when it was mostly two lane, but prefer it now, but not between DC to Boston. We make this round trip between Florida and Maine every year and I've tried just about all the options.