San Antonio to Nova Scotia--what shouldn't we miss?

Try to take in the Blue Ridge Parkway, starting from Cherokee, NC, and go up thru Ashville, (Stop and see the Biltmore). When you get to the end of the Parkway at Waynesboro, just keep going on to the Skyline Drive in Shenandoah National Park. You can splinter off from there and do a side trip to Williamsburg, a good day trip and see Monticello also.
If you get to Bar Harbor, there is a ferry that takes you to Yarmouth, Nova Scotia, a great way to start your Canada trip.
So much to see.....so little time!