What wintersun said. Except Sequoia National Park is only on the west side of the Sierras...no connection from the east side during your time frame...and you don't need to go all the way to Barstow to get to the 58.
So, when heading north on the 15 you can take the 215 if you want, but it's probably just as easy to just stay on the 15 until you get over Cajon Pass and then head north on 395.
Hitting the 395 right after Cajon Pass instead of going all the way to Barstow will save you about 40 miles. There will be some congestion on the 395 around the outskirts of Victorville/Adelanto (several stop lights, but once past Adelanto, it's clear sailing. About 40 miles past Adelanto, you will come to the junction of 395/58 at Kramer Jct, you will need to turn left on the 58 and go towards Bakersfield (over Tehachapi pass...no big deal unless it is snowing) and to the 99.
The alternate is to take the 15 to the 215 (or again just stay on the 15), to the 210. Go west on the 210 until you get to the 5. This route will skirt the LA proper, and the 5 will take you over the Grapevine (again, not a big deal unless it is snowing). Once over the Grapevine, take 99 north through Bakersfield and on up to the turnoff to Sequoia Nat Park.
A word to the wise, if it is snowing in Southern California, stay off of the Grapevine, Tehachapi, and Cajon Passes.
Good luck and I hope this helps
Ron
