San Fransico to San Diego without going through LA?

If you take 395 from 58 southbound, be aware that there are some steep grades, and it is mostly a heavily travelled 2 lane road that is notorious for head on collisions -- too many folks in a big hurry to pass.

But it still might be faster than struggling through urban LA -- from Castaic to Camp Pendleton is 120 miles of solid urban slogging. Fun!!