I believe I would take US 287 (Wichita Falls, Amarillo, Dumas) to US 87 (Dalhart, Clayton, Raton) to I-25 N to US 160 (Walsenburg, Alamosa, Monte Vista).
Enroute Sites & Sights:
Could take a detour, somewhat Southwest of Quanah:
Caprock Canyons State Park & Trailway would make a neat place to check out. One I would like to see.
Ditto,
Copper Breaks State Park near Quanah sounds pretty cool. But not much of a detour for it.
Dumas City Park north of Amarillo. Or the
Amarillo Welcome CenterMore overnighting along
US 287 between Dallas/Fort Worth Area to Amarillo.
In New Mexico. Between Clayton & Raton is the Capulin Volcano Nat'l Mon't.
A Neat Place. ------
But no CampingNear Clayton,
Clayton Lake State Park. Never been to it, however.
Sugarite Canyon State Park by Raton is a neat area.
On return trip, one could drop down to Sante Fe via US 285 S from Alamosa.
Lot of neat things to see & do in the
Santa Fe Area in New MexicoUsing US 285 S from Santa Fe (off I-25) will take one to I-40 E, then back to Amarillo & US 287.
I-25 N (Just East of Santa Fe) just pasted the US 285 exit, in the Glorieta Pass & Pecos Area:
Civil War Battlefield and
Pecos Nat'l Historic Park, the remains of an Indian pueblo.
Off I-25 between Santa Fe & Las Vegas, NM,
Villanueva State Park. It is off the 25 a bit. Somewhat off the beaten path.
Near Santa Rosa just Off I-40,
Santa Rosa Lake State Park would be another nice place to overnight. Never been there myself.