We drove that section just once in April of last year ! After flying up and purchasing our Class C in Ohio, we were headed to the Staunton Va area. Having never driven an RV in the mountains (or at all) I found that section to be no issue. We actually spent the night at the Beckley Service plaza ( after a recommendation from this forum). Sandstone Mt was also a non issue ( even for this Flat lander) and we saw some pretty areas through there !
You should have no issues, just enjoy the trip !