How necessary (or not) reservations are varies greatly with when and where you're looking to go. Popular campgrounds in major tourist destinations during high seasons or holidays absolutely positively do require reservations. Ordinary campgrounds in ordinary places during less popular times generally do not require reservations, though occasionally what may seem like not especially popular places or times could turn out to be the week of the annual Earthworm Farmer's Convention and Skateboard Race that draws skateboarding earthworm farmers out of the woodwork from far and wide, and they all stay at the local campgrounds.
Generally, though, it's not essential to have reservations for non-holidays, non-tourist destinations, especially on weekdays, and doubly so if you're willing and able to be a little flexible about where you camp.