Last time I was on the road this past January there was 6 to 8 inches of lose sand on much of the road. Road conditions vary greatly, be prepared for everything. I would certainly not camp along the road. I would plan to make the trip in one day and camp in the Ajo area after the day trip. I would certainly not discourage you from the adventure, just don't stop for anyone other than the border patrol. They will tell you the same thing. You may see one person, but if you stop a bunch may just be in hiding. The name Devils Highway is a good description, and road conditions are probably 100% better today than when the settlers used it. I can not even imagine the hardships those many years ago.