I can help with route from Palo Duro to Durango. You've chosen the most benign route ie: not much in the way of elevation changes. No super hairy curves, pulls or downhill's. There is a short steep hill going into Durango on 550 but nothing that easy going won't take care of. There is a fairly steep hill(not long either) going into Palo Duro Canyon but well worth it. In Amarillo we enjoyed the Quarter Horse Museum and the Big Texan. In Albuquerque there is lot's to see. We have a Tram that takes you to the top of Sandia Mountain 10,673 ft., Old Town Plaza, recently people have been visiting to take 'The Breaking Bad' tour, we have several nearby Indian Pueblo's, we have 4 Casino's if you're into gambling, lot's of places to eat, several microbreweries. In Durango, there is Steam train that goes from Durango to Silverton, a great ride something not to miss, we love Durango it is just a quaint mountain town.
A caution or safety note. Please keep in mind the elevation. When you get to Albuquerque you will be just about a mile high, so you may feel short of breath and more tired than usual. Drink plenty of water this will help, give yourself time to acclimatize before hiking up a mountain or even a steep hill even if you are fit. You'll be over 6,500 ft in Durango. Otherwise, have a great time!
Sheila aka...