We did in June between I-84 and I-80 (Scranton to Harrisburg). It was miserable. Coming from Ontario, I don't know if there's a good alternate. 15 maybe?
If you get on google maps, and put in where you are going to, it will give you a up-to-date timely construction/accident report of your route. I looked at I-81 from Ottawa to Tampa and it was just packed full of construction icons on I-81 and also on I-95.
Some of our Canadian friends going to Florida have gone either on I 90 west to I 79 through PA etc.
Or through Ohio on I 75 etc. this adds a little bit of time, but a more pleasant drive. Take a look on Google maps, from Buffalo, and see what you think. ( sorry I did not know your final destination)
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