We made that trip in 2014. Spent a couple of days in Ocala visiting friends. From there went to Fort Myers beach. Stayed at Red Coconut, visited Sanibal island. Then we headed to the Keys. Stayed at Jolly Rogers campground in Marathon. That was about halfway on the keys. Visited almost all of the islands. Spent most of the time at Key West though. Then headed up the Atlantic coast. Made a stop in Orange to see relatives. They took us to Blue Springs but did not see the Manatees. From there went to Fort Pierce for a few days. Traveled back and forth to Daytona Beach. This is probably the nicest beach we ever been on. Then on to Jacksonville to visit a friend before heading back North.
Should have made a few more stops but needed to get back home to get the RV worked on before warranty ran out.