There are 2 types of vinyl floors being discussed here. One is the click together style that is designed to be a floating floor and is not meant to be glued down. If you want to replace a section, you pretty well have to take the floor apart. The other type is glue down that is not click together. A section can be fairly easily replaced by using a heat gun to release the glue. I have experience with both types in house renovations, and I much prefer the glue down type. Waterproof, durable and easy to clean, this type would be my recommendation.