We spend a lot of time on the road, as do so many here, and I see a lot of trailers being pulled everywhere by 1/2 ton trucks. I must admit that the majority seem to be bumper pulls rather than 5th wheels, but I still see a lot of them.
I tried it some years back and found if I stayed on relatively flat ground, I was comfortable towing in all aspects but as soon as we made one trip up highway 395 to Mammoth Lakes I realized what a huge mistake it was. I literally felt bad for my poor truck. I strained in 1st and 2nd gear to go up grades and worried about coming down them. As soon as we returned I sold my 1/2 ton and found a great deal on my 3/4 ton diesel. It wasn't a month later I traded the trailer on something bigger! Go figure.
1/2 ton with Terry 5th:


3/4 ton with same trailer which I had to flip the axles:

3/4 ton with new trailer:

See how that works?