I've owned Ram 3500 Dually since 2010, all had 4.10, This 16 has the Aisin with 4.10. I've towed up to speeds of 70mph, normally, 65 mph. Towed on flat land in Louisiana, Mississippi and Texas and for the first time in my life could actually say, "I didn't even know it was back there". Towing in the mountains in WV, TN, VA, NC and SC, you know it's back there, but I've towed 7% grades on Interstates in WV & VA and on some secondary roads in VA , TN and WV, on curvy , mountainous roads with 10-15% grades at times.. truck handles all well.. GCW SCALED IS 28,250#. Thus the reason I have the 4.10 with the Aisin. Never have heard the truck "screaming" because of the load its towing . Going on 18K and never an issue. When I ordered the 4.10, I thought about the 3.73, but decided on the 4.10. I'd say 3.73, under the right application would be the best of both worlds between the 3.42 and the 4.10. Just my opinion, depending on applications and weight one is going to tow.
Jim