We take our two cats with us all the time. And will be full-time rving with them when the house sells. We started them young. One of our cats gets car sick in the pickup (pickup sick?) but has no problem with the 5er. They both crawl under our bedcovers when it's time to leave. Some people would say we need to put them in a cage....that stresses them more than the off-chance there is an accident. Watch for them when you bring the slides in. I'd start car training them now.....a short trip then build up to a long trip. It's not a problem at all for us!!!!!