I've carried 2 Ultra's cross country several times. Before I started I double checked all the factory tie-downs. They were predominantly wood screws and not gonna cut it. I replaced them with through bolts, large washers and lock-nuts. I used thread-locker on all. I figured it was my bike and my responsibility and the best insurance was a good defense.
To date, no issues. Take a little time to go the extra mile. You'll be a lot more relaxed if you know how things are tied down and to what.
Happy Camping!!