The only issue I had to deal with when I got our '17 last year was with the hitch. We had the standard bed rails in our previous truck and the new Ford has the puck system. We have a Trailer Saver BD3 air ride hitch and no way am I giving it up so I had to get an adapter. I bought the Reese without doing much research since I needed it quickly. I didn't realize it would raise the height of my hitch by 3 3/8" compared to the 1 3/8" of the old bed rails (measured from the bed floor). I was able to lower the hitch about an inch and a half to it's lowest setting which helped but still sit just a bit nose high, but not enough to be a concern. My pin box is already at it's highest setting so no help there.
Just something to consider.
