Sorry, but less 5er or more truck. A 2500 is at safe limit with about a 12-14k 5er & 2k pin. Remember to include cargo and passengers in truck loading.
A 3500srw can handle a 16k 5er, for more than that a dually.
I see hundreds of units every year in every concievable match up. The biggest thing I hear is ' we wish we had more truck' . Then rv size & weight is no problem.
If you can, stay shorter with longer slides to keep gvw and pin box weights down, get elec. over hydraulic brakes. Make the rigs brakes equal to the truck.
Yes there are many hundreds who say here in camp and in forum that their truck handles it just fine. My concern is about your life, and ours. Too little truck, too mich camper puts more than your life at risk.
Start out right.