Get some shelf liner that is kind of non-skid. There is a Rubbermaid version that has little bumps on it, that helps a lot.
No need to pack/unpack. Just don't put heavy thinks--like a gallon of water--next to your crackers or bread. Kind of keep like items together. Get some plastic or Corelle plates, and mostly plastic drinking glasses, etc.
Anything that's glass and relatively fragile, like the glass portion of a coffeepot, should be in a cabinet with some towels or something wrapped around the glass portion so it doesn't slide around much.
Electronics travel nicely in the middle of the bed, for anything you don't want/need in your tow vehicle.
Make sure your liquids in the fridge are closed tightly. You may find that a few small things in the fridge slide around but it's not generally a big deal.