I'm pushing 67 this year and am always looking for something really new and revolutionary in the RV industry. Sadly I have not found anything that is a fit for me that is better what I have.
As far as my fiver, I'm in a Rockwood Signature Ultralight 8288SS, and it is simple to set up solo with no problem whatsoever. One of the biggest advantages of that particular unit for me is that it has dual opposing slides which makes the inside of the rig really large and spacious feeling. The opposing slides in a rear living arrangement is the most important thing for me these days - large windows for view in the parks I favor, which are mostly backing up to the water on the coastline.
As to truck, I'm using a 6.7L 3500 Cummins (not that truck brand matters), but I'm fond of having a large heavy powerful truck (way overkill for my 8k dry trailer). I barely feel the rig behind me and average a reasonable 12mpg.
I guess the take home lesson is that everyone will have their own idea of the "perfect" truck/rig combination. Ask yourself the important questions like internal trailer space including layout (many of the rigs we see have the television 90 degrees from the seats which makes for a sore neck at the end of the day), comfort towing without experiencing semi blow-by, etc.