We've owned four 5th wheels and are on our second motor home; and have full-timed in both. For us, we prefer the motorhome - it's nice to have access to everything while going down the road, even to the point of making a cup of coffee in the Keurig. But, and it's a big one, if you're looking for less maintenance and higher mileage, a fiver is your best bet. A motor home comparable to a good-sized fiver will of probably be a DP, and they're more expensive to buy and maintain, and the mileage is about half of what a diesel pickup will get.