A couple of points to check are the fuel pressure regulator, I think they may have changed it up some in 05 or 06, but on my 02 model it is at the back of the engine on the drivers side by the fuel rail. There is no fuel pressure sensor in the 8.1 so the computer assumes the fuel pressure regulator is doing its job, and assumes the fuel pressure is always right. So a vacuum leak or a bad fuel pressure regulator could cause the fuel trim to go bad. Also check the spark plug wires, the 8.1L vortec is notorious for burning through spark plug wires if the coach manufacturer did not provide enough ventilation to the engine compartment.