All in how much you'll be traveling with it.
Fiver is best for livability by and far. You'll also have a better floor plan selection.
MH is best when you're on the road.
Ask yourself how much will you be on the road, get a number and then compare that to how much you'll be setup.
Setup. I see people act like a MH is so much easier. They all can have auto levelers, poop hose, power hose, water hose etc. Fifth hitches are much easier and faster to drop than a toad. Backing in a fiver is more difficult but is easy once you learn to not over turn the truck while backing. They are more of a wash if you ask me unless you are adverse to learning how to back up correctly.
Truck vs toad. Each has benefits although the toad is the better around town. Is it THAT MUCH BETTER? I really don't think so. Then again I drive a decent sized motor home so the truck is pretty tiny comparatively. Really not a big deal its one of those over blown benefits.
Best way to pick is to count the days you'll be on the road. My guess is it will be tiny. Compare to how many days you'll be in the unit and then decide if you want livability or on the road comfort. With the exception of the toilet you can bring most of that comfort in a cooler or in a portable tablet / tv / blu ray.
Of course you have the "but its a CLASS A" crowd who equate some kind of status with their rig. If you might be one of those then maybe you don't want to be a filthy peasant in a towable. Personally i think its ridiculous.
