The EB V6 is close to the V-10's numbers... but not there yet. It has a great power curve, flat like a diesel, but can it replace the V-10? As above, it doesn't have the same duty cycle. It makes a Ford F-150 or Transit fun to drive, but it is not going to be happy trying to handle 20,000+ pounds of stuff.
I think Ford is going to wind up adding two cylinders to the EB and using that, just like the two cylinders added to the 5.4 got us the V-10. This will produce more horses and torque than the old V-10, but have the size to handle 30,000+ pounds of GCWR. I hope Ford does this, because the biggest thing people bash the V-10 for is that it is normally aspirated, so loses power at higher elevations. Having a set of turbos would not just help here, but help with MPG generally.
As RobertRyan stated, diesels are what the rest of the world is moving to, but the US is still a gasoline holdout, mainly because of the corn lobby selling ethanol, diesel engines are still expensive here ($6-8k more than gas counterparts), and there is still a negative sentiment about diesels in the US (they are viewed as slow, smelly, and require a lot of maintenance. Even though all that is not true these days, it still persists.)