If the coach in question will only support 30A service and is older, then it will be able to only run 1 at a time. If its newer and has some kind of a power management module, then it will likely be able to run both (switching). If it is ducted, then you could run 1 and force some of the air to the back (assuming that it is ducted that way). But, in a hot enviroment, I suspect that you'll be unhappy with the results (both front and back).
We had an older 30A coach prior to what we have now and it could run only 1 AC unit when hooked to shore power (both were powered when it was running via the generator).
We would shut the door to the bathroom during the day (which was right in front of the bedroom) and it would keep the front half cool. At night, I would switch AC units. That arrangement pretty much did not work for me as it generally took an hour or so to completely cool things and it never really kept the coach as cool as I would prefer. And, during the day the bathroom was always hot.
So, I actually made a change to the RV and wired up a means to allow me to run the rear AC unit on a separate 20A circuit. Once I did that, it worked well. The campgrounds we went to had both a 30A and a 20A circuit (separate) that allowed this to work. Once I had that, I was happy as a clam with the temperature in the RV (my wife even complained that it got too cold).
On a coach that supports 50A service, you can run both of them all the time.
Regardless of what the coach has currently and if you go anywhere south in the summertime, you will want and need to run both units. We did not enjoy our trips as much when we had just 1 AC unit available.