I have no experience of RV sealing as only just purchasing our first unit, so greatly interested in this subject. Good to read the above quote on Types of sealant and compatibility.
I come from the marine industry and large high speed car carrying catamarans where we used Sikaflex. So far I have not seen anyone mention this on a forum. Whilst expensive it has superb sealing capabilities and flexibility (I have seen the window glass moving in the frame during heavy sea conditions as the structure flexs with no leaks as the water hits the windows. The biggest problem is taking anything apart that has been sealed with sikaflex due to its adhesion. Sikaflex 291 is for marine use, including underwater and there is a sikaflex 221 in the Uk that is used for caravans/RV, but I have not used it. Suggest you look up on www.sika.com Unfortunately at this present time their web site fact sheets are not working for these products :(