I drive I80 every 2-3 years as I buy diesel cars and occasionally motorhomes on east coast and drive them to California.
In short IT IS BORING
I stop at Little America for internet connection and 99 cents ice cream cones, but not much more.
In Nebraska there is huge overpass that makes agricultural museum, but it is open on weekends only and I never found the door open.
One time taking wife with me have visited John Deere museum. A bit annoying as the first sign said "turn out here" than 1 mile later next sign says "3 miles and then right" then next sign....
Funny to learn John Deere was a blacksmith and died 50 years before tractor got invented.