Our previous rig, a Coachmen Freelander 3150SS, had a pair of overflow/vent pipes that were attached to the top-rear of the fresh water tank. We travel to many remote dark sky sites for astronomy and need every drop we can haul to some of the sites.
Several of the sites to which we regularly travel, Mt. Pinos, CA, Camp Oakes near Big Bear, CA, and Grandview Campground, CA (in the Sierras) among others, are at the top of very steep grades. In that rig which had a relatively small fresh water tank to begin with, water would flow out of the overflow when we went up steep grades and I'd often arrive at a site with only 2/3 of our fresh water supply. Water would even slop out when backing out of our long and relatively steep driveway.
My solution...was to install PVC ball valves onto the ends of the overflow/vent pipes. (Slip connectors glued onto the rigid overflow pipes the other end threaded into the valves.) After filling the tank, I'd close the valves and only open them when we arrived at our destination. Labels on the dash and adjacent to the water pump switch(es) reminded me to open the valves when we reached our destination.