One interesting pro for the Ford chassis models. Ten years from now, you will be able to find parts for the E-350/E-450 chassis, including crate engines.
Because Mercedes is killing the diesel Sprinter, it may be dicey finding things like particulate filters and such, ten years from now. It might be that parts would only be available from a "boutique" custom CNC machining place, similar to how people obtain parts for long-discontinued VW stuff.
I personally am concerned about parts availability with Sprinters, especially with this recent announcement, so I would look at another chassis if buying within the next couple years, until this mess is sorted out. On the other hand, I have zero worries with Fords if I need to find something.
