Maybe, maybe not, depending on where your gearing puts you on the torque curve for the speeds you run, and whether HP is adequate at the OD rpm and highway speed. It might even take a gearing change to optimize for the OD ratio.
The idea is right, have more gears to work with, but new cars with 6-8 speeds also have a fly by wire and a computer optimizing gears and throttle to your demands at the accelerator. With a TH and add on UD/OD you might have 5-6 gears to work with, some of them very close to each other, but you'd still lack the information needed to pick the right gear.
Will it pay? Maybe if you get it right and can run 500,000 to a couple million miles to save enough on fuel to pay for it.