If it is getting into 3rd gear it should be running at the RPMs General Motors thought it needs to be running to pull the loads it is specified to pull. It should be geared for about 2600 to 3000 RPM at highway speeds, a little more than that to top speed.
You could get RPMs down about 20-30% by installing an aftermarket overdrive, but then it might be struggling to maintain 55 mph, and shifting in and out of OD to maintain that speed. A lot will depend on grade and wind speed and direction. A 0.80 overdrive tends to be more useful in the 60-70 mph range, where RPMs are back up high enough to generate the HP needed to go that fast.
You are not going to cruise 55 mph at 1000-1200 RPM in a gas motorhome, the way you do in a modern V-6 or V-8 passenger car, which has an engine capable of putting out six to ten times the power needed to maintain highway cruising speed.
Same thing in sub-compacts, engines sized closer to actual need. My Honda Fit turns 2750 in top gear at 55 MPH, 3200 to 3600 RPM at my usual highway speeds. My small-engine pickup truck is in the same RPM range.
Saying it is "screaming" if running at that speed is confusing. Makes us think you might be stuck in second gear, running 4000 RPM.
If you are turning a fan, the fan noise will be very loud at RPMs as low as 2000. At 55 mph, unless you've just finished climbing a 10 mile 6% grade, the fan should be freewheeling. The designed failure mode for thermostatic fan clutches is to engage the fan. Maybe you need a new fan clutch?